AUTISM CAUSES
Autism is a complex developmental disability. Experts believe autism presents itself during the first three years of the life of a person. The condition is the result of a neurological disorder that affects normal brain function, affecting the development of a person's communication and social interaction skills. People with autism have problems with nonverbal communication, a wide range of social interactions and activities that involve an element of play and / or teasing.
Autism is not having a single identifiable cause. Given the complexity of the disease, the prevalence of symptoms of autism and the fact that no two children with autism are alike, there are probably many reasons. These may include:
Long believed that there is a common cause of genetics, cognitive and neural levels of the triad of symptoms of autism. However, there is a growing suspicion that autism is a complex disorder whose core instead of causes other issues that often are concurrent.
Autism has a very strong genetic problem, because the genetics of autism are complex and its not clear whether ASD is explained more by rare mutations with large effects on the global interaction or multiple rare between common genetic variants. The complexity is that interactions between multiple genes, environmental factors and epigenetic modifications that do not alter DNA, but is hereditary and affects the expression of genes.
Autism is a complex developmental disability. Experts believe autism presents itself during the first three years of the life of a person. The condition is the result of a neurological disorder that affects normal brain function, affecting the development of a person's communication and social interaction skills. People with autism have problems with nonverbal communication, a wide range of social interactions and activities that involve an element of play and / or teasing.
Autism is not having a single identifiable cause. Given the complexity of the disease, the prevalence of symptoms of autism and the fact that no two children with autism are alike, there are probably many reasons. These may include:
Long believed that there is a common cause of genetics, cognitive and neural levels of the triad of symptoms of autism. However, there is a growing suspicion that autism is a complex disorder whose core instead of causes other issues that often are concurrent.
Autism has a very strong genetic problem, because the genetics of autism are complex and its not clear whether ASD is explained more by rare mutations with large effects on the global interaction or multiple rare between common genetic variants. The complexity is that interactions between multiple genes, environmental factors and epigenetic modifications that do not alter DNA, but is hereditary and affects the expression of genes.
Studies of twins indicate that heredity is 0.7 for autism and as high as 0.9 for ASD and siblings of people with autism is about 25 times more likely to be autistic population General. But most of the mutations that increase risk of autism have not been identified. Typically, autism is not due to a Mendelian (gene) mutation or a chromosomal abnormality, such as fragile X syndrome, and none of the genetic syndromes associated with ASD has been demonstrated to cause selective ASD.
Several candidate genes are located, is only a small effect on the outcome of a particular gene. A large number of people with autism does not affect the family may be due to variation in copy number, spontaneous deletion or duplication of genetic material during meiosis. Consequently, a substantial proportion of cases of autism may be traced to genetic causes, which are highly heritable but not inherited, that is mutations that cause autism is not present in the genome of the child.
Several candidate genes are located, is only a small effect on the outcome of a particular gene. A large number of people with autism does not affect the family may be due to variation in copy number, spontaneous deletion or duplication of genetic material during meiosis. Consequently, a substantial proportion of cases of autism may be traced to genetic causes, which are highly heritable but not inherited, that is mutations that cause autism is not present in the genome of the child.
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